With DNA being considered the blue print of life, every biological function is well coded in our genes. This DNA which dictates every clinical activity within the body is packed in chromosomes within every cell. Every healthy human being is born with a definite number of chromosomes i.e. 22 pairs of autosomes and 1 pair of sex chromosomes. This totals to the presence of 46 chromosomes in genetically healthy individuals

Normal Males - 44 autosomes + X Y Sex chromosomes.

Normal Females - 44 autosomes + X X Sex chromosomes.

Cytogenetics
Significance
Sample Requirement
Techniques
Advantages
Why Thyrocare

ABOUT CYTOGENETICS

Cytogenetics refers to the study of number and structure of chromosomes within cells. Since chromosomes contain highly coiled DNA, any structural or numerical changes in these directly affect function of genes, resulting in genetic defects/disorders. Cytogenetics is a highly specialized branch of medical science which involves culture of various biological tissues/fluids (peripheral blood, bone marrow, abortus tissue, prenatal tissue), harvesting of cell culture for chromosome preparation, differential stainings (e.g. GTG banding), analysis and reporting of the results. Cytogenetic studies can identify the underlying causes of multiple defects which affect the developing fetus, neonates, children as well as adults. Popularly used techniques under cytogenetics involve Karyotyping and FISH (Fluorescent In-situ Hybridization)
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